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Gene Information
Gene symbol: KIF16B
Gene name: kinesin family member 16B
HGNC ID: 15869
Synonyms: FLJ20135, dJ971B4.1, SNX23
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | KIF21A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 34274317 | Some genetic mutations identified in NS patients cause amino acid substitutions of kidney ankyrin repeat-containing (KANK) proteins, which are scaffold proteins that regulate actin polymerization, microtubule targeting, and cell adhesion via binding to various molecules, including the kinesin motor protein KIF21A. |
| 2 | 34274317 | Biochemical and structural analyses revealed that the pathological mutation induces abnormal binding of eIF4A1 to KANK2 at the physiological KIF21A-binding site. |
| 3 | 34274317 | Competitive binding assays further indicated that eIF4A1 can compete with KIF21A to interact with the S684F mutant of KANK2. |
| 4 | 34274317 | In cultured mouse podocytes, this S684F mutant interfered with the KANK2/KIF21A interaction by binding to eIF4A1, and failed to rescue the focal adhesion or cell adhesion that had been reduced or morphologically changed by KANK2 knockout. |