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Gene Information
Gene symbol: MCC
Gene name: mutated in colorectal cancers
HGNC ID: 6935
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD2AP | 1 hits |
| 2 | JUP | 1 hits |
| 3 | WT1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 34926519 | To experimentally prove the essentiality of MCC for podocytes, we knocked down MCC in cultured podocytes and found marked morphological change of cell shape, cytoskeletal F-actin stress fiber disruption, increased apoptosis, and downregulation of podocyte essential genes, CD2AP and WT1, demonstrating that MCC is essential for podocytes. |
| 2 | 34926519 | Since MCC has been implicated in cell cycle and β-catenin signaling, we examined the expression of cell cycle related genes and activity of β-catenin in the MCC knockdown podocytes, but did not find significant changes. |
| 3 | 34926519 | To experimentally prove the essentiality of MCC for podocytes, we knocked down MCC in cultured podocytes and found marked morphological change of cell shape, cytoskeletal F-actin stress fiber disruption, increased apoptosis, and downregulation of podocyte essential genes, CD2AP and WT1, demonstrating that MCC is essential for podocytes. |
| 4 | 34926519 | Since MCC has been implicated in cell cycle and β-catenin signaling, we examined the expression of cell cycle related genes and activity of β-catenin in the MCC knockdown podocytes, but did not find significant changes. |