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Gene Information
Gene symbol: MCM7
Gene name: minichromosome maintenance complex component 7
HGNC ID: 6950
Synonyms: CDC47
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | MIRN93 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20501654 | Identification of microRNA-93 as a novel regulator of vascular endothelial growth factor in hyperglycemic conditions. |
| 2 | 20501654 | Here, we provide evidence that microRNA-93 (miR-93) regulates VEGF expression in experimental models of diabetes both in vitro and in vivo. |
| 3 | 20501654 | We identified VEGF-A as a putative target of miR-93 in the kidney with a perfect complementarity between miR-93 and the 3'-untranslated region of vegfa in several species. |
| 4 | 20501654 | We showed that forced expression of miR-93 in cells abrogated VEGF protein secretion. |
| 5 | 20501654 | Conversely, anti-miR-93 inhibitors increased VEGF release. |
| 6 | 20501654 | Transfection of miR-93 also prevented the effect of high glucose on VEGF downstream targets. |
| 7 | 20501654 | Using transgenic mice containing VEGF-LacZ bicistronic transcripts, we found that inhibition of glomerular miR-93 by peptide-conjugated morpholino oligomers elicited increased expression of VEGF. |
| 8 | 20501654 | Our findings also indicate that high glucose decreases miR-93 expression by down-regulating the promoter of the host MCM7 gene. |
| 9 | 20501654 | Taken together, our findings provide new insights into the role of miR-93 in VEGF signaling pathway and offer a potentially novel target in preventing the progression of diabetic nephropathy. |