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Gene Information
Gene symbol: MFN2
Gene name: mitofusin 2
HGNC ID: 16877
Synonyms: CPRP1, KIAA0214, MARF, CMT2A2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | DNM1L | 1 hits |
| 2 | DNM3 | 1 hits |
| 3 | FIS1 | 1 hits |
| 4 | KEAP1 | 1 hits |
| 5 | KHDRBS1 | 1 hits |
| 6 | MAP1LC3A | 1 hits |
| 7 | MFN1 | 1 hits |
| 8 | NFE2L2 | 1 hits |
| 9 | OPA1 | 1 hits |
| 10 | PINK1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 33796024 | Expressions of mitochondrial dynamics-related and autophagy-related proteins, such as Mfn2, Fis1, P62, and LC3, as well as Nrf2, Keap1, PINK1, and Parkin, were examined by immunohistochemistry, western blot, and real-time PCR, respectively. |
| 2 | 33796024 | AS II also partially restored the renal expression of mitochondrial dynamics-related and autophagy-related proteins, including Mfn2, Fis1, P62, and LC3. |
| 3 | 33796024 | These results suggested that AS II ameliorated podocyte injury and mitochondrial dysfunction in diabetic rats partly through regulation of Nrf2 and PINK1 pathway. |
| 4 | 33796024 | Expressions of mitochondrial dynamics-related and autophagy-related proteins, such as Mfn2, Fis1, P62, and LC3, as well as Nrf2, Keap1, PINK1, and Parkin, were examined by immunohistochemistry, western blot, and real-time PCR, respectively. |
| 5 | 33796024 | AS II also partially restored the renal expression of mitochondrial dynamics-related and autophagy-related proteins, including Mfn2, Fis1, P62, and LC3. |
| 6 | 33796024 | These results suggested that AS II ameliorated podocyte injury and mitochondrial dysfunction in diabetic rats partly through regulation of Nrf2 and PINK1 pathway. |
| 7 | 34437881 | Podocytes that were treated with HG showed a fragmented mitochondrial network, together with a decrease in expression of the mitochondrial fusion markers MFN1, MFN2, and OPA1, and an increase in the activity of the fission marker DRP1. |
| 8 | 34988075 | Mitofusin2 (Mfn2) was initially identified as a dynamin-like protein involved in fusing the outer mitochondrial membrane (OMM). |
| 9 | 34988075 | Streptozotocin (STZ)-induced diabetic rats exhibited abnormal mitochondrial morphology and MAMs reduction in podocytes, accompanied by decreased expression of Mfn2 and activation of all three unfolded protein response (UPR) pathways (IRE1, ATF6, and PERK). |