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Gene Information
Gene symbol: MYL2
Gene name: myosin, light chain 2, regulatory, cardiac, slow
HGNC ID: 7583
Synonyms: CMH10
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CDH5 | 1 hits |
| 2 | FLT4 | 1 hits |
| 3 | KDR | 1 hits |
| 4 | MYH14 | 1 hits |
| 5 | VEGFC | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 18772335 | We have previously reported expression of vascular endothelial growth factor (VEGF)-A and -C in glomerular podocytes and actions of VEGF-A on glomerular endothelial cells (GEnC) that express VEGF receptor-2 (VEGFR-2). |
| 2 | 18772335 | Here we define VEGFR-3 expression in GEnC and investigate the effects of the ligand VEGF-C. |
| 3 | 18772335 | VEGF-C effects on trans-endothelial electrical resistance and albumin flux across GEnC monolayers were measured. |
| 4 | 18772335 | VEGF-C effects on intracellular calcium ([Ca2+]i) were measured using a fluorescence technique, receptor phosphorylation was examined by immunoprecipitation assays, and phosphorylation of myosin light chain-2 and VE-cadherin was assessed by blotting with phospho-specific antibodies. |
| 5 | 18772335 | GEnC expressed VEGFR-3 in tissue sections and culture, and VEGF-C increased trans-endothelial electrical resistance in a dose-dependent manner with a maximal effect at 120 minutes of 6.8 Omega whereas VEGF-C156S had no effect. |
| 6 | 18772335 | VEGF-C reduced labeled albumin flux by 32.8%. |
| 7 | 18772335 | VEGF-C and VEGF-A increased [Ca2+]i by 15% and 39%, respectively. |
| 8 | 18772335 | VEGF-C phosphorylated VEGFR-2 but not VEGFR-3, myosin light chain-2, or VE-cadherin. |
| 9 | 18772335 | These observations suggest that podocytes direct GEnC behavior through both VEGF-C and VEGF-A. |
| 10 | 18772335 | We have previously reported expression of vascular endothelial growth factor (VEGF)-A and -C in glomerular podocytes and actions of VEGF-A on glomerular endothelial cells (GEnC) that express VEGF receptor-2 (VEGFR-2). |
| 11 | 18772335 | Here we define VEGFR-3 expression in GEnC and investigate the effects of the ligand VEGF-C. |
| 12 | 18772335 | VEGF-C effects on trans-endothelial electrical resistance and albumin flux across GEnC monolayers were measured. |
| 13 | 18772335 | VEGF-C effects on intracellular calcium ([Ca2+]i) were measured using a fluorescence technique, receptor phosphorylation was examined by immunoprecipitation assays, and phosphorylation of myosin light chain-2 and VE-cadherin was assessed by blotting with phospho-specific antibodies. |
| 14 | 18772335 | GEnC expressed VEGFR-3 in tissue sections and culture, and VEGF-C increased trans-endothelial electrical resistance in a dose-dependent manner with a maximal effect at 120 minutes of 6.8 Omega whereas VEGF-C156S had no effect. |
| 15 | 18772335 | VEGF-C reduced labeled albumin flux by 32.8%. |
| 16 | 18772335 | VEGF-C and VEGF-A increased [Ca2+]i by 15% and 39%, respectively. |
| 17 | 18772335 | VEGF-C phosphorylated VEGFR-2 but not VEGFR-3, myosin light chain-2, or VE-cadherin. |
| 18 | 18772335 | These observations suggest that podocytes direct GEnC behavior through both VEGF-C and VEGF-A. |