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Gene Information

Gene symbol: NOTCH4

Gene name: notch 4

HGNC ID: 7884

Related Genes

#	Gene Symbol	Number of hits
1	CCL2	1 hits
2	GORASP1	1 hits
3	IL6	1 hits
4	NFKB1	1 hits
5	NOTCH1	1 hits
6	PSEN1	1 hits
7	S100B	1 hits
8	SIRT6	1 hits

Related Sentences

#	PMID	Sentence
1	28871079	Sirt6 also reduces urokinase plasminogen activator receptor expression, which is a key factor for podocyte foot process effacement and proteinuria.
2	28871079	Mechanistically, Sirt6 inhibits Notch1 and Notch4 transcription by deacetylating histone H3K9.
3	31727625	Using luciferase reporter assays, we did not observe activation of the NOTCH4 promoter with the HIV protein Nef in podocytes.
4	31727625	Further, we observed upregulated expression of a gamma secretase complex protein, presenilin 1, but not Notch4, in podocytes infected with an HIV-1 expression construct.
5	31727625	Consistent with the diminished inflammation, kidneys from Notch4d1/Tg26+ mice also showed a significant decrease in expression of the inflammatory cytokine transcripts Il-6 and Ccl2, as well as the master inflammatory transcription factor NF-κB (Nfkb1 transcripts and p65 protein).
6	31727625	Using luciferase reporter assays, we did not observe activation of the NOTCH4 promoter with the HIV protein Nef in podocytes.
7	31727625	Further, we observed upregulated expression of a gamma secretase complex protein, presenilin 1, but not Notch4, in podocytes infected with an HIV-1 expression construct.
8	31727625	Consistent with the diminished inflammation, kidneys from Notch4d1/Tg26+ mice also showed a significant decrease in expression of the inflammatory cytokine transcripts Il-6 and Ccl2, as well as the master inflammatory transcription factor NF-κB (Nfkb1 transcripts and p65 protein).
9	31727625	Using luciferase reporter assays, we did not observe activation of the NOTCH4 promoter with the HIV protein Nef in podocytes.
10	31727625	Further, we observed upregulated expression of a gamma secretase complex protein, presenilin 1, but not Notch4, in podocytes infected with an HIV-1 expression construct.
11	31727625	Consistent with the diminished inflammation, kidneys from Notch4d1/Tg26+ mice also showed a significant decrease in expression of the inflammatory cytokine transcripts Il-6 and Ccl2, as well as the master inflammatory transcription factor NF-κB (Nfkb1 transcripts and p65 protein).