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Gene Information
Gene symbol: NT5E
Gene name: 5'-nucleotidase, ecto (CD73)
HGNC ID: 8021
Synonyms: CD73, eN, eNT
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CCR2 | 1 hits |
| 2 | CD24 | 1 hits |
| 3 | CD8A | 1 hits |
| 4 | CXCL2 | 1 hits |
| 5 | ENG | 1 hits |
| 6 | ENTPD2 | 1 hits |
| 7 | IL18 | 1 hits |
| 8 | IL2RA | 1 hits |
| 9 | ITGAM | 1 hits |
| 10 | MCAM | 1 hits |
| 11 | PAX2 | 1 hits |
| 12 | PROM1 | 1 hits |
| 13 | THY1 | 1 hits |
| 14 | VEGFA | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21163251 | Neither ecto-ATPase nor ecto-5'-nucleotidase activities were affected in HG. |
| 2 | 22610571 | We recently found that human glomeruli deprived of the Bowman's capsule contain a population of CD133(-)CD146(+) cells that coexpress the typical mesenchymal stem cells (MSCs) markers (such as CD29, CD105, and CD73) and renal specific stem cell markers (such us CD24 and Pax2). |
| 3 | 22666342 | We observed autoimmune inflammation in CD73(-/-)mice with glomerulitis and peritubular capillaritis, showing glomerular deposition of IgG and C3 and enhanced presence of CD11b, CD8, CD25 as well as GR-1-positive cells in the interstitium. |
| 4 | 22666342 | Vascular inflammation was associated with enhanced serum levels of the cytokines IL-18 and TNF-α as well as VEGF and the chemokine MIP-2 (CXCL-2) in CD73(-/-)mice, whereas chemokines and cytokines in the kidney tissue were unaltered or reduced. |
| 5 | 22666342 | We observed autoimmune inflammation in CD73(-/-)mice with glomerulitis and peritubular capillaritis, showing glomerular deposition of IgG and C3 and enhanced presence of CD11b, CD8, CD25 as well as GR-1-positive cells in the interstitium. |
| 6 | 22666342 | Vascular inflammation was associated with enhanced serum levels of the cytokines IL-18 and TNF-α as well as VEGF and the chemokine MIP-2 (CXCL-2) in CD73(-/-)mice, whereas chemokines and cytokines in the kidney tissue were unaltered or reduced. |
| 7 | 26062877 | These cells surrounded vessels and coexpressed the pericyte markers CD73 and CD146, but not the endothelial marker ERG. |
| 8 | 31191670 | Furthermore, these cells express the typical MSC markers CD73, CD90, and CD105. |
| 9 | 31191670 | Immunofluorescence-based stainings of sectioned 3D-NPCs revealed cells expressing the renal progenitor cell markers (SIX2 and PAX8), podocyte markers (Nephrin and Podocin), the endothelial marker (CD31), and mesenchymal markers (Vimentin and PDGFR-β). |
| 10 | 34299260 | We assessed the expression of CD73 and one of its functionally important targets, the C-C chemokine receptor type 2 (CCR2), in podocytes from kidney biopsies of 39 patients with podocytopathy (including focal segmental glomerulosclerosis (FSGS), minimal change disease (MCD), membranous glomerulonephritis (MGN) and amyloidosis) and a control group. |
| 11 | 34299260 | Moreover, there was a marked negative correlation between CD73 and CCR2 expression, as confirmed by immunohistochemistry and immunofluorescence (Pearson r = -0.5068, p = 0.0031; Pearson r = -0.4705, p = 0.0313, respectively), thus suggesting a protective role of CD73 in kidney injury. |