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Gene Information
Gene symbol: PCSK9
Gene name: proprotein convertase subtilisin/kexin type 9
HGNC ID: 20001
Synonyms: NARC-1, FH3
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CNBP | 1 hits |
| 2 | COG2 | 1 hits |
| 3 | LDLR | 1 hits |
| 4 | SCAP | 1 hits |
| 5 | SREBF2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 27019638 | To maintain a cholesterol homeostasis, LDLR expression is tightly regulated by sterol regulatory element-binding protein-2 (SREBP-2) and SREBP cleavage-activating protein (SCAP) in transcriptional level and by proprotein convertase subtilisin/kexin type 9 (PCSK9) in posttranscriptional level. |
| 2 | 27019638 | It has been demonstrated that inflammation, renin-angiotensin system (RAS) activation, and hyperglycemia induce the disruption of LDLR pathway, which might contribute to lipid disorder-mediated organ injury (atherosclerosis, non-alcoholic fatty liver disease, kidney fibrosis, etc). |
| 3 | 31157893 | Protein convertase subtilisin/kexin type 9 (PCSK9) [accelerates LDL-receptor (LDL-R) degradation] is overexpressed by liver cells in NS. |
| 4 | 31157893 | This article explores the established and forthcoming evidence implicating PCSK9 in LDL-C dysregulation in NS. |
| 5 | 31157893 | Protein convertase subtilisin/kexin type 9 (PCSK9) [accelerates LDL-receptor (LDL-R) degradation] is overexpressed by liver cells in NS. |
| 6 | 31157893 | This article explores the established and forthcoming evidence implicating PCSK9 in LDL-C dysregulation in NS. |