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Gene Information
Gene symbol: PDCD4
Gene name: programmed cell death 4 (neoplastic transformation inhibitor)
HGNC ID: 8763
Synonyms: H731
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | MIRN21 | 1 hits |
| 2 | SMAD3 | 1 hits |
| 3 | SMAD7 | 1 hits |
| 4 | TGFBR2 | 1 hits |
| 5 | TIMP3 | 1 hits |
| 6 | TP53 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 25145934 | In cultured podocytes, inhibition of miR-21 was accompanied by increases in the rate of cell death, TGF-β/Smad3-signaling activity, and expression of known proapoptotic miR-21 target genes p53, Pdcd4, Smad7, Tgfbr2, and Timp3. |
| 2 | 25145934 | In American-Indian patients with diabetic nephropathy (n=48), albumin-to-creatinine ratio was positively associated with miR-21 expression in glomerular fractions (r=0.6; P<0.001) but not tubulointerstitial fractions (P=0.80). |
| 3 | 25145934 | The aggravation of glomerular disease in miR-21-deficient mice and the positive association with albumin-to-creatinine ratio in patients with diabetic nephropathy support miR-21 as a feedback inhibitor of TGF-β signaling and functions. |