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Gene Information
Gene symbol: PDGFRB
Gene name: platelet-derived growth factor receptor, beta polypeptide
HGNC ID: 8804
Synonyms: JTK12, CD140b, PDGFR1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CCL2 | 1 hits |
| 2 | CCL5 | 1 hits |
| 3 | CCR2 | 1 hits |
| 4 | COL1A1 | 1 hits |
| 5 | MCAM | 1 hits |
| 6 | NOTCH3 | 1 hits |
| 7 | NPHS1 | 1 hits |
| 8 | NPHS2 | 1 hits |
| 9 | PAX8 | 1 hits |
| 10 | PDGFA | 1 hits |
| 11 | PDGFD | 1 hits |
| 12 | PECAM1 | 1 hits |
| 13 | REN | 1 hits |
| 14 | SIX2 | 1 hits |
| 15 | VIM | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 31191670 | Furthermore, these cells express the typical MSC markers CD73, CD90, and CD105. |
| 2 | 31191670 | Immunofluorescence-based stainings of sectioned 3D-NPCs revealed cells expressing the renal progenitor cell markers (SIX2 and PAX8), podocyte markers (Nephrin and Podocin), the endothelial marker (CD31), and mesenchymal markers (Vimentin and PDGFR-β). |
| 3 | 26017974 | In addition to segmental and global glomerulosclerosis in older mice, staining for matrix proteins collagen type IV and heparan sulfate proteoglycan were markedly increased in Bowman's capsules of older mouse glomeruli, consistent with increased extracellular matrix production by PECs. |
| 4 | 26017974 | The mural cell markers neural/glial antigen 2, PDGF receptor-β, and CD146 as well as Notch 3 were also substantially increased in aged PECs. |
| 5 | 24904091 | Intraglomerular renin descendant LacZ-expressing cells colocalized with mesangial cell markers α8-integrin and PDGF receptor-β but not with endothelial, podocyte, or parietal epithelial cell markers. |
| 6 | 21866094 | Induction of progressive glomerulonephritis by podocyte-specific overexpression of platelet-derived growth factor-D. |
| 7 | 21866094 | Platelet-derived growth factor-D (PDGF-D), normally expressed in podocytes, mediates mesangial cell proliferation in vivo. |
| 8 | 21866094 | Renal mRNA expression of podocin and nephrin, as well as the number of glomerular WT-1-positive cells, were significantly reduced in hemizygous compared to wild-type mice, indicating loss and/or dedifferentation of podocytes. |
| 9 | 21866094 | PDGF-A, -B, and both PDGF receptor chain mRNAs, fibronectin, type IV collagen, RANTES, MCP-1, and CCR-2 mRNAs were all increased in the renal cortex of PDGF-D transgenic mice. |