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Gene Information
Gene symbol: PITX2
Gene name: paired-like homeodomain 2
HGNC ID: 9005
Synonyms: IGDS, RS, Brx1, Otlx2, ARP1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ASCL1 | 1 hits |
| 2 | FIGLA | 1 hits |
| 3 | RGS4 | 1 hits |
| 4 | TFAP2C | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15914773 | Using MDCK cells that stably express regulators of G protein-signaling (RGS) proteins [RGS4 attenuates Galpha(i) and Galpha(q), and the p115RhoGEF-RGS domain (p115-RGS) attenuates Galpha(12/13)] to define the signaling pathway, we found that mechanical force induced Galpha(12/13)-Rho activation and increased F-actin to stimulate PLD activity. |
| 2 | 30696889 | The first set - FIGLA, PITX2, ASCL1 and TFAP2C, differentiated hPSCs into SIX2+SALL1+ nephron progenitor cells with 92% efficiency within 2 days. |
| 3 | 30696889 | Subsequently, the second set - HNF1A, GATA3, GATA1 and EMX2, differentiated these cells into PAX8+LHX1+ pretubular aggregates in another 2 days. |