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Gene Information
Gene symbol: PKHD1
Gene name: polycystic kidney and hepatic disease 1 (autosomal recessive)
HGNC ID: 9016
Synonyms: ARPKD, FCYT
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
26740740
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Induced pluripotent stem cells (iPSCs) are somatic cells that have been transcriptionally reprogrammed to an embryonic stem cell (ESC)-like state. iPSCs are a renewable source of diverse somatic cell types and tissues matching the original patient, including nephron-like kidney organoids. iPSCs have been derived representing several kidney disorders, such as ADPKD, ARPKD, Alport syndrome, and lupus nephritis, with the goals of generating replacement tissue and 'disease in a dish' laboratory models.
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