Ignet

Gene Information

Gene symbol: PRDX2

Gene name: peroxiredoxin 2

HGNC ID: 9353

Synonyms: PRP, NKEFB, TSA, PRXII, PRX2, MGC4104

Related Genes

#	Gene Symbol	Number of hits
1	AGT	1 hits
2	AKT1	1 hits

Related Sentences

#	PMID	Sentence
1	21814176	Downregulation of the antioxidant protein peroxiredoxin 2 contributes to angiotensin II-mediated podocyte apoptosis.
2	21814176	Sustained renin-angiotensin-aldosterone system activation is crucial to the pathogenesis of podocyte injury, but the mechanisms by which angiotensin II modulates podocyte survival due to physiological or injurious stimuli remain unclear.
3	21814176	Antioxidant protein peroxiredoxin 2 expression was decreased in cultured podocytes stimulated with angiotensin II.
4	21814176	Peroxiredoxin 2 was found to be expressed in podocytes in vivo, and its expression was decreased in the glomeruli of rats transgenic for angiotensin II type 1 receptors in a podocyte-specific manner, or in rats infused with angiotensin II.
5	21814176	Downregulation of peroxiredoxin 2 in podocytes resulted in increased reactive oxygen species release, protein overoxidation, and inhibition of the Akt pathway.
6	21814176	Both treatment with angiotensin II and downregulation of peroxiredoxin 2 expression led to apoptosis of podocytes.
7	21814176	Thus, peroxiredoxin 2 is an important modulator of angiotensin II-induced podocyte injury.
8	21814176	Downregulation of the antioxidant protein peroxiredoxin 2 contributes to angiotensin II-mediated podocyte apoptosis.
9	21814176	Sustained renin-angiotensin-aldosterone system activation is crucial to the pathogenesis of podocyte injury, but the mechanisms by which angiotensin II modulates podocyte survival due to physiological or injurious stimuli remain unclear.
10	21814176	Antioxidant protein peroxiredoxin 2 expression was decreased in cultured podocytes stimulated with angiotensin II.
11	21814176	Peroxiredoxin 2 was found to be expressed in podocytes in vivo, and its expression was decreased in the glomeruli of rats transgenic for angiotensin II type 1 receptors in a podocyte-specific manner, or in rats infused with angiotensin II.
12	21814176	Downregulation of peroxiredoxin 2 in podocytes resulted in increased reactive oxygen species release, protein overoxidation, and inhibition of the Akt pathway.
13	21814176	Both treatment with angiotensin II and downregulation of peroxiredoxin 2 expression led to apoptosis of podocytes.
14	21814176	Thus, peroxiredoxin 2 is an important modulator of angiotensin II-induced podocyte injury.
15	21814176	Downregulation of the antioxidant protein peroxiredoxin 2 contributes to angiotensin II-mediated podocyte apoptosis.
16	21814176	Sustained renin-angiotensin-aldosterone system activation is crucial to the pathogenesis of podocyte injury, but the mechanisms by which angiotensin II modulates podocyte survival due to physiological or injurious stimuli remain unclear.
17	21814176	Antioxidant protein peroxiredoxin 2 expression was decreased in cultured podocytes stimulated with angiotensin II.
18	21814176	Peroxiredoxin 2 was found to be expressed in podocytes in vivo, and its expression was decreased in the glomeruli of rats transgenic for angiotensin II type 1 receptors in a podocyte-specific manner, or in rats infused with angiotensin II.
19	21814176	Downregulation of peroxiredoxin 2 in podocytes resulted in increased reactive oxygen species release, protein overoxidation, and inhibition of the Akt pathway.
20	21814176	Both treatment with angiotensin II and downregulation of peroxiredoxin 2 expression led to apoptosis of podocytes.
21	21814176	Thus, peroxiredoxin 2 is an important modulator of angiotensin II-induced podocyte injury.
22	21814176	Downregulation of the antioxidant protein peroxiredoxin 2 contributes to angiotensin II-mediated podocyte apoptosis.
23	21814176	Sustained renin-angiotensin-aldosterone system activation is crucial to the pathogenesis of podocyte injury, but the mechanisms by which angiotensin II modulates podocyte survival due to physiological or injurious stimuli remain unclear.
24	21814176	Antioxidant protein peroxiredoxin 2 expression was decreased in cultured podocytes stimulated with angiotensin II.
25	21814176	Peroxiredoxin 2 was found to be expressed in podocytes in vivo, and its expression was decreased in the glomeruli of rats transgenic for angiotensin II type 1 receptors in a podocyte-specific manner, or in rats infused with angiotensin II.
26	21814176	Downregulation of peroxiredoxin 2 in podocytes resulted in increased reactive oxygen species release, protein overoxidation, and inhibition of the Akt pathway.
27	21814176	Both treatment with angiotensin II and downregulation of peroxiredoxin 2 expression led to apoptosis of podocytes.
28	21814176	Thus, peroxiredoxin 2 is an important modulator of angiotensin II-induced podocyte injury.
29	21814176	Downregulation of the antioxidant protein peroxiredoxin 2 contributes to angiotensin II-mediated podocyte apoptosis.
30	21814176	Sustained renin-angiotensin-aldosterone system activation is crucial to the pathogenesis of podocyte injury, but the mechanisms by which angiotensin II modulates podocyte survival due to physiological or injurious stimuli remain unclear.
31	21814176	Antioxidant protein peroxiredoxin 2 expression was decreased in cultured podocytes stimulated with angiotensin II.
32	21814176	Peroxiredoxin 2 was found to be expressed in podocytes in vivo, and its expression was decreased in the glomeruli of rats transgenic for angiotensin II type 1 receptors in a podocyte-specific manner, or in rats infused with angiotensin II.
33	21814176	Downregulation of peroxiredoxin 2 in podocytes resulted in increased reactive oxygen species release, protein overoxidation, and inhibition of the Akt pathway.
34	21814176	Both treatment with angiotensin II and downregulation of peroxiredoxin 2 expression led to apoptosis of podocytes.
35	21814176	Thus, peroxiredoxin 2 is an important modulator of angiotensin II-induced podocyte injury.
36	21814176	Downregulation of the antioxidant protein peroxiredoxin 2 contributes to angiotensin II-mediated podocyte apoptosis.
37	21814176	Sustained renin-angiotensin-aldosterone system activation is crucial to the pathogenesis of podocyte injury, but the mechanisms by which angiotensin II modulates podocyte survival due to physiological or injurious stimuli remain unclear.
38	21814176	Antioxidant protein peroxiredoxin 2 expression was decreased in cultured podocytes stimulated with angiotensin II.
39	21814176	Peroxiredoxin 2 was found to be expressed in podocytes in vivo, and its expression was decreased in the glomeruli of rats transgenic for angiotensin II type 1 receptors in a podocyte-specific manner, or in rats infused with angiotensin II.
40	21814176	Downregulation of peroxiredoxin 2 in podocytes resulted in increased reactive oxygen species release, protein overoxidation, and inhibition of the Akt pathway.
41	21814176	Both treatment with angiotensin II and downregulation of peroxiredoxin 2 expression led to apoptosis of podocytes.
42	21814176	Thus, peroxiredoxin 2 is an important modulator of angiotensin II-induced podocyte injury.