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Gene Information
Gene symbol: PRKAR2B
Gene name: protein kinase, cAMP-dependent, regulatory, type II, beta
HGNC ID: 9392
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
12408047
|
This autoimmunity may result from loss of a feedback inhibitory pathway in which Lyn phosphorylates CD22, triggering recruitment of the tyrosine phosphatase SHP-1 to the plasma membrane, which then dampens BCR signaling.
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2 |
12408047
|
Loss of Lyn also compromises an inhibitory pathway involving Fc gamma RIIb and SHIP, an inositol phosphatase.
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