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Gene Information

Gene symbol: PTH2

Gene name: parathyroid hormone 2

HGNC ID: 30828

Synonyms: TIP39

Related Genes

# Gene Symbol Number of hits
1 PTH 1 hits

Related Sentences

# PMID Sentence
1 9121603 The first receptor which has been cloned and well characterized is "PTH/PTHrP receptor-1".
2 9121603 It is activated not only by PTH, but also by PTH-related peptide (PTHrP), via a signal transduction system involving G-proteins, adenylate cyclase and phospholipase C.
3 9121603 One or several receptors are probably expressed in the keratinocyte and the glomerular podocyte which are not identical with PTH/ PTHrP receptor-1.
4 9121603 A third receptor, which has been cloned recently and called "PTH2 receptor", recognizes solely PTH.
5 9121603 There is also evidence for a fourth receptor, called "C-PTH receptor", recognizing C-terminal PTH fragments which are generally considered to be biologically inactive.
6 9121603 Down-regulation of PTH/PTHrP receptor-1 mRNA expression could explain the well-known resistance to the action of PTH in chronic renal failure.
7 9121603 A mutation of PTH/PTHrP receptor-1 causes Jansen-type metaphyseal chondrodysplasia.
8 9121603 However, no alteration of the PTH/PTHrP receptor-1 gene structure has been found in type 1b pseudohypoparathyroidism.