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Gene Information

Gene symbol: PTPRU

Gene name: protein tyrosine phosphatase, receptor type, U

HGNC ID: 9683

Synonyms: PTPRO, hPTP-J, PCP-2, FMI, PTP

Related Genes

# Gene Symbol Number of hits
1 PTPRB 1 hits
2 PTPRH 1 hits
3 PTPRJ 1 hits
4 PTPRO 1 hits

Related Sentences

# PMID Sentence
1 7519601 The first such protein characterized (designated glomerular epithelial protein 1 (GLEPP1)) is a membrane protein-tyrosine phosphatase (PTPase) with a large extracellular domain containing eight fibronectin type III-like repeats, a hydrophobic transmembrane segment, and a single PTPase domain.
2 7519601 The GLEPP1 PTPase domain shows homology with two other single domain transmembrane PTPases (PTP beta and Drosophila central nervous system PTP10D).
3 20633639 The R3 subtype of receptor-type protein tyrosine phosphatases (RPTPs) includes VE-PTP, DEP-1, PTPRO, and SAP-1.
4 20633639 The expression of each R3 RPTP is largely restricted to a single or limited number of cell types, with VE-PTP and DEP-1 being expressed in endothelial or hematopoietic cells, PTPRO in neurons and in podocytes of the renal glomerulus, and SAP-1 in gastrointestinal epithelial cells.
5 20633639 The R3 subtype of receptor-type protein tyrosine phosphatases (RPTPs) includes VE-PTP, DEP-1, PTPRO, and SAP-1.
6 20633639 The expression of each R3 RPTP is largely restricted to a single or limited number of cell types, with VE-PTP and DEP-1 being expressed in endothelial or hematopoietic cells, PTPRO in neurons and in podocytes of the renal glomerulus, and SAP-1 in gastrointestinal epithelial cells.
7 31984788 CD148 is a transmembrane protein tyrosine phosphatase (PTP) that is expressed in the renal vasculature, including the glomerulus.
8 31984788 Previous studies have shown that CD148 plays a role in the negative regulation of growth factor signals (including epidermal growth factor and vascular endothelial growth factor), suppressing cell proliferation and transformation.
9 31984788 The mAbs that increased CD148 activity were selected by biological (proliferation) and biochemical (PTP activity) assays.
10 31984788 CD148 is a transmembrane protein tyrosine phosphatase (PTP) that is expressed in the renal vasculature, including the glomerulus.
11 31984788 Previous studies have shown that CD148 plays a role in the negative regulation of growth factor signals (including epidermal growth factor and vascular endothelial growth factor), suppressing cell proliferation and transformation.
12 31984788 The mAbs that increased CD148 activity were selected by biological (proliferation) and biochemical (PTP activity) assays.