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Gene Information
Gene symbol: RARRES3
Gene name: retinoic acid receptor responder (tazarotene induced) 3
HGNC ID: 9869
Synonyms: TIG3, HRASLS4
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
23296190
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In addition to these receptors, Toll-like receptor 3 (TLR3) and retinoic acid-inducible gene 1 (RIG-I)-like helicases (RLHs), podocytes express the collateral proteins required to support intracellular signaling.
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2 |
23296190
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The transcription factor interferon regulatory factor 3 (IRF3) and nuclear factor kappa B (NF-ĸB) are phosphorylated and translocate to the nucleus, and dsRNA increases synthesis of proteins driven by IRF3 (P54, P56 and P60) or NF-ĸB (interleukin 8 and A20).
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3 |
23296190
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Furthermore, dsRNA suppresses podocyte cell migration, alters the expression of a panel of podocyte essential proteins (nephrin, podocin and CD2-associated protein or CD2AP) and changes transepithelial albumin flux.
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