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Gene Information

Gene symbol: RCA1

Gene name: renal carcinoma, familial, associated 1

HGNC ID: 9929

Related Genes

# Gene Symbol Number of hits
1 ACTC1 1 hits
2 DES 1 hits
3 EZH2 1 hits
4 PPP2R4 1 hits
5 SOSTDC1 1 hits

Related Sentences

# PMID Sentence
1 1753704 Endothelial and mesangial cells were positively identified from the early cultures (up to 10 days) with antibodies to a 350 kD protein, dipeptidyl peptidase IV, podocalyxin, factor VIII, OX-43 and with Bandeiraea simplicifolia (BS-I B4) lectin, and with antibodies to smooth muscle actin, desmin, Thy1.1 antigens and with Ricinus communis (RCA-1) lectin, respectively.
2 18032587 Because SOSTDC1 suppresses proliferation of renal carcinoma cells, restoration of SOSTDC1 signaling may represent a novel target in treatment of renal clear cell carcinoma.
3 33679454 Enhancer of zeste homolog 2 (EZH2) is a histone-lysine N-methyltransferase enzyme that catalyzes the addition of methyl groups to histone H3 at lysine 27, leading to gene silencing.
4 33679454 Mutation or over-expression of EZH2 has been linked to many cancers including renal carcinoma.
5 34539832 Protein phosphatase 2A (PP2A), which is involved in renal development and the function of ion-transport proteins, aquaporin-2 and podocytes, is likely to serve an important role in renal processes.
6 34539832 How dysregulation of PP2A in the kidneys causes podocyte death and the inactivation of PP2A in renal carcinoma tissues is discussed.