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Gene Information
Gene symbol: RPS6KB1
Gene name: ribosomal protein S6 kinase, 70kDa, polypeptide 1
HGNC ID: 10436
Synonyms: S6K1, p70(S6K)-alpha, PS6K
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CRTC1 | 1 hits |
| 2 | JUN | 1 hits |
| 3 | MAP1LC3A | 1 hits |
| 4 | PRKCA | 1 hits |
| 5 | RORC | 1 hits |
| 6 | UBASH3B | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21228102 | Both GSK3 inhibitors reduced the phosphorylation of the mTOR downstream target, p70(S6K), indicating that GSK3 inhibition in podocytes is able to cause similar effects as treatment with rapamycin. |
| 2 | 33303821 | Saturated fatty acids induce insulin resistance in podocytes through inhibition of IRS1 via activation of both IKKβ and mTORC1. |
| 3 | 33303821 | Our results demonstrate that saturated FFA activated the serine/threonine kinases IκB kinase (IKK)β/IκBα and mTORC1/S6K1, but not protein kinase C and c-jun N-terminal kinase, in podocytes and glomeruli of db/db mice. |
| 4 | 33303821 | Using IKK, mTORC1 and ceramide production inhibitors, we were able to blunt IRS1 serine 307 phosphorylation and restore insulin stimulation of Akt. |
| 5 | 34408785 | Yiqi Huoxue Recipe Regulates Autophagy through Degradation of Advanced Glycation End Products via mTOR/S6K1/LC3 Pathway in Diabetic Nephropathy. |