Ignet

Gene Information

Gene symbol: SALL1

Gene name: sal-like 1 (Drosophila)

HGNC ID: 10524

Synonyms: Hsal1, ZNF794

Related Genes

#	Gene Symbol	Number of hits
1	ALDH1A2	1 hits
2	FGF8	1 hits
3	FOXC2	1 hits
4	FOXD1	1 hits
5	GDNF	1 hits
6	HSPA5	1 hits
7	LMX1B	1 hits
8	MAFB	1 hits
9	NPC1	1 hits
10	NPHS2	1 hits
11	OSR2	1 hits
12	PAX2	1 hits
13	PAX8	1 hits
14	PDGFC	1 hits
15	SIX2	1 hits
16	SYNPO	1 hits
17	TCF21	1 hits
18	WNT4	1 hits
19	WT1	1 hits

Related Sentences

#	PMID	Sentence
1	15172686	We detected many genes known to be important for metanephros development including Sall1, GDNF, Raldh2, Pax8 and FoxD1, and genes expressed abundantly in the metanephric mesenchyme such as Unc4.1, Six2, Osr-2 and PDGFc.
2	15172686	We also found groups of genes including SSB-4, Smarcd3, micro-Crystallin, TRB-2, which are not known to be expressed in the metanephric mesenchyme.
3	26154924	WT1 controls metanephric mesenchyme (MM) self-renewal and proliferation mainly by regulating FGF and BMP-pSMAD signaling pathways as well as Sall1 and Pax2, encoding key transcription factors; WT1 drives MM differentiation and mesenchyme-epithelial transition by targeting Fgf8 and Wnt4; WT1 defines podocyte identity by activation of other podocyte-specific transcription factors, including Mafb, Lmx1b, FoxC2, and Tcf21.
4	26458176	By recapitulating metanephric kidney development in vitro, we generate SIX2+ SALL1+ WT1+ PAX2+ NPCs with 90% efficiency within 9 days of differentiation.
5	28759006	To explore the significance of Sall1 in differentiated podocytes, we investigated podocyte-specific Sall1-deficient mice (Sall1 KO^p°^d°^/p°^d°) using a podocin-Cre/loxP system and siRNA Sall1 knockdown (Sall1 KD) podocytes.
6	28759006	Differentiated Sall1 KD podocytes showed a loss of synaptopodin, suppressed stress fiber formation, and, ultimately, impaired directed cell migration.
7	28759006	These results indicated that Sall1 has a protective role in podocytes; thus, we investigated the endoplasmic reticulum stress marker GRP78.
8	28759006	GRP78 expression was higher in ADR-treated Sall1 KO^p°^d°^/p°^d° mice than in control mice.
9	28759006	Sall1 appeared to influence the expression of GRP78 in injured podocytes.
10	28759006	To explore the significance of Sall1 in differentiated podocytes, we investigated podocyte-specific Sall1-deficient mice (Sall1 KO^p°^d°^/p°^d°) using a podocin-Cre/loxP system and siRNA Sall1 knockdown (Sall1 KD) podocytes.
11	28759006	Differentiated Sall1 KD podocytes showed a loss of synaptopodin, suppressed stress fiber formation, and, ultimately, impaired directed cell migration.
12	28759006	These results indicated that Sall1 has a protective role in podocytes; thus, we investigated the endoplasmic reticulum stress marker GRP78.
13	28759006	GRP78 expression was higher in ADR-treated Sall1 KO^p°^d°^/p°^d° mice than in control mice.
14	28759006	Sall1 appeared to influence the expression of GRP78 in injured podocytes.
15	28759006	To explore the significance of Sall1 in differentiated podocytes, we investigated podocyte-specific Sall1-deficient mice (Sall1 KO^p°^d°^/p°^d°) using a podocin-Cre/loxP system and siRNA Sall1 knockdown (Sall1 KD) podocytes.
16	28759006	Differentiated Sall1 KD podocytes showed a loss of synaptopodin, suppressed stress fiber formation, and, ultimately, impaired directed cell migration.
17	28759006	These results indicated that Sall1 has a protective role in podocytes; thus, we investigated the endoplasmic reticulum stress marker GRP78.
18	28759006	GRP78 expression was higher in ADR-treated Sall1 KO^p°^d°^/p°^d° mice than in control mice.
19	28759006	Sall1 appeared to influence the expression of GRP78 in injured podocytes.
20	28759006	To explore the significance of Sall1 in differentiated podocytes, we investigated podocyte-specific Sall1-deficient mice (Sall1 KO^p°^d°^/p°^d°) using a podocin-Cre/loxP system and siRNA Sall1 knockdown (Sall1 KD) podocytes.
21	28759006	Differentiated Sall1 KD podocytes showed a loss of synaptopodin, suppressed stress fiber formation, and, ultimately, impaired directed cell migration.
22	28759006	These results indicated that Sall1 has a protective role in podocytes; thus, we investigated the endoplasmic reticulum stress marker GRP78.
23	28759006	GRP78 expression was higher in ADR-treated Sall1 KO^p°^d°^/p°^d° mice than in control mice.
24	28759006	Sall1 appeared to influence the expression of GRP78 in injured podocytes.
25	28759006	To explore the significance of Sall1 in differentiated podocytes, we investigated podocyte-specific Sall1-deficient mice (Sall1 KO^p°^d°^/p°^d°) using a podocin-Cre/loxP system and siRNA Sall1 knockdown (Sall1 KD) podocytes.
26	28759006	Differentiated Sall1 KD podocytes showed a loss of synaptopodin, suppressed stress fiber formation, and, ultimately, impaired directed cell migration.
27	28759006	These results indicated that Sall1 has a protective role in podocytes; thus, we investigated the endoplasmic reticulum stress marker GRP78.
28	28759006	GRP78 expression was higher in ADR-treated Sall1 KO^p°^d°^/p°^d° mice than in control mice.
29	28759006	Sall1 appeared to influence the expression of GRP78 in injured podocytes.