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Gene Information
Gene symbol: SERPINF1
Gene name: serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
HGNC ID: 8824
Synonyms: EPC-1, PIG35
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | IGF1 | 1 hits |
| 2 | INS | 1 hits |
| 3 | NPHS1 | 1 hits |
| 4 | PNPLA2 | 1 hits |
| 5 | PPARG | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17497179 | In the adult kidney, one of the major inhibitors of angiogenesis is pigment-epithelium-derived factor (PEDF). |
| 2 | 19042927 | Administration of pigment epithelium-derived factor (PEDF) reduces proteinuria by suppressing decreased nephrin and increased VEGF expression in the glomeruli of adriamycin-injected rats. |
| 3 | 23108227 | PEDF inhibits AGE-induced podocyte apoptosis via PPAR-gamma activation. |
| 4 | 23108227 | Recently, we, along with others, have found that pigment epithelium-derived factor (PEDF), a glycoprotein with potent neuronal differentiating activity, inhibits AGE-elicited mesangial and tubular cell damage through its anti-oxidative properties. |
| 5 | 23108227 | PEDF inhibits AGE-induced podocyte apoptosis via PPAR-gamma activation. |
| 6 | 23108227 | Recently, we, along with others, have found that pigment epithelium-derived factor (PEDF), a glycoprotein with potent neuronal differentiating activity, inhibits AGE-elicited mesangial and tubular cell damage through its anti-oxidative properties. |
| 7 | 23884140 | Protective role of small pigment epithelium-derived factor (PEDF) peptide in diabetic renal injury. |
| 8 | 23884140 | Pigment epithelium-derived factor (PEDF) is a multifunctional protein with antiangiogenic, antioxidative, and anti-inflammatory properties. |
| 9 | 23884140 | Protective role of small pigment epithelium-derived factor (PEDF) peptide in diabetic renal injury. |
| 10 | 23884140 | Pigment epithelium-derived factor (PEDF) is a multifunctional protein with antiangiogenic, antioxidative, and anti-inflammatory properties. |
| 11 | 27683034 | Our model showed that, treatment with pigment epithelium derived factor (PEDF) or insulin-like growth factor-1 (IGF-1) alone merely ameliorated the glomerulus injury, while co-treatment with both cytokines replenished the damaged podocyte population gradually. |
| 12 | 27683034 | These results indicated that amelioration of the glomerular stress by PEDF and promotion of PEC differentiation by IGF-1 are equivalently critical for podocyte regeneration. |
| 13 | 27683034 | Our model showed that, treatment with pigment epithelium derived factor (PEDF) or insulin-like growth factor-1 (IGF-1) alone merely ameliorated the glomerulus injury, while co-treatment with both cytokines replenished the damaged podocyte population gradually. |
| 14 | 27683034 | These results indicated that amelioration of the glomerular stress by PEDF and promotion of PEC differentiation by IGF-1 are equivalently critical for podocyte regeneration. |