Ignet

Gene Information

Gene symbol: SOSTDC1

Gene name: sclerostin domain containing 1

HGNC ID: 21748

Synonyms: DKFZp564D206, USAG1

Related Genes

#	Gene Symbol	Number of hits
1	CTGF	1 hits
2	RCA1	1 hits
3	SMAD1	1 hits
4	SYNPO	1 hits

Related Sentences

#	PMID	Sentence
1	18032587	Because SOSTDC1 suppresses proliferation of renal carcinoma cells, restoration of SOSTDC1 signaling may represent a novel target in treatment of renal clear cell carcinoma.
2	19255250	Extracellular antagonists such as connective tissue growth factor (CTGF; CCN-2) and sclerostin domain-containing-1 (SOSTDC1; USAG-1) are important determinants of BMP signaling activity in glomeruli.
3	19255250	BMP signaling activity was visualized by phosphorylated Smad1, -5, and -8 (pSmad1/5/8) immunostaining, and related to expression of CTGF, SOSTDC1, and the podocyte differentiation markers WT1, synaptopodin, and nephrin.
4	19255250	Nephrin and synaptopodin were decreased in diabetic glomeruli.
5	19255250	SOSTDC1 and CTGF were expressed exclusively in podocytes.
6	19255250	In diabetic glomeruli, SOSTDC1 decreased in parallel with podocyte number, whereas CTGF was strongly increased.
7	19255250	This might relate to concomitant overexpression of CTGF but not SOSTDC1.
8	19255250	Extracellular antagonists such as connective tissue growth factor (CTGF; CCN-2) and sclerostin domain-containing-1 (SOSTDC1; USAG-1) are important determinants of BMP signaling activity in glomeruli.
9	19255250	BMP signaling activity was visualized by phosphorylated Smad1, -5, and -8 (pSmad1/5/8) immunostaining, and related to expression of CTGF, SOSTDC1, and the podocyte differentiation markers WT1, synaptopodin, and nephrin.
10	19255250	Nephrin and synaptopodin were decreased in diabetic glomeruli.
11	19255250	SOSTDC1 and CTGF were expressed exclusively in podocytes.
12	19255250	In diabetic glomeruli, SOSTDC1 decreased in parallel with podocyte number, whereas CTGF was strongly increased.
13	19255250	This might relate to concomitant overexpression of CTGF but not SOSTDC1.
14	19255250	Extracellular antagonists such as connective tissue growth factor (CTGF; CCN-2) and sclerostin domain-containing-1 (SOSTDC1; USAG-1) are important determinants of BMP signaling activity in glomeruli.
15	19255250	BMP signaling activity was visualized by phosphorylated Smad1, -5, and -8 (pSmad1/5/8) immunostaining, and related to expression of CTGF, SOSTDC1, and the podocyte differentiation markers WT1, synaptopodin, and nephrin.
16	19255250	Nephrin and synaptopodin were decreased in diabetic glomeruli.
17	19255250	SOSTDC1 and CTGF were expressed exclusively in podocytes.
18	19255250	In diabetic glomeruli, SOSTDC1 decreased in parallel with podocyte number, whereas CTGF was strongly increased.
19	19255250	This might relate to concomitant overexpression of CTGF but not SOSTDC1.
20	19255250	Extracellular antagonists such as connective tissue growth factor (CTGF; CCN-2) and sclerostin domain-containing-1 (SOSTDC1; USAG-1) are important determinants of BMP signaling activity in glomeruli.
21	19255250	BMP signaling activity was visualized by phosphorylated Smad1, -5, and -8 (pSmad1/5/8) immunostaining, and related to expression of CTGF, SOSTDC1, and the podocyte differentiation markers WT1, synaptopodin, and nephrin.
22	19255250	Nephrin and synaptopodin were decreased in diabetic glomeruli.
23	19255250	SOSTDC1 and CTGF were expressed exclusively in podocytes.
24	19255250	In diabetic glomeruli, SOSTDC1 decreased in parallel with podocyte number, whereas CTGF was strongly increased.
25	19255250	This might relate to concomitant overexpression of CTGF but not SOSTDC1.
26	19255250	Extracellular antagonists such as connective tissue growth factor (CTGF; CCN-2) and sclerostin domain-containing-1 (SOSTDC1; USAG-1) are important determinants of BMP signaling activity in glomeruli.
27	19255250	BMP signaling activity was visualized by phosphorylated Smad1, -5, and -8 (pSmad1/5/8) immunostaining, and related to expression of CTGF, SOSTDC1, and the podocyte differentiation markers WT1, synaptopodin, and nephrin.
28	19255250	Nephrin and synaptopodin were decreased in diabetic glomeruli.
29	19255250	SOSTDC1 and CTGF were expressed exclusively in podocytes.
30	19255250	In diabetic glomeruli, SOSTDC1 decreased in parallel with podocyte number, whereas CTGF was strongly increased.
31	19255250	This might relate to concomitant overexpression of CTGF but not SOSTDC1.