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Gene Information
Gene symbol: STAP2
Gene name: signal transducing adaptor family member 2
HGNC ID: 30430
Synonyms: STAP-2, BKS
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
29038896
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Compared with the control (C57 or BKS), ATF3 expression was elevated in animal model of proteinuria (LPS-treated C57 mice) and the model of diabetic nephropathy (db/db mice).
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2 |
29038896
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Overexpression of ATF3 increased podocyte apoptosis and decreased expression of podocin, the cell marker of podocyte; in contrast, ATF3-small interfering RNA knockdown reduced podocyte apoptosis and increased podocin expression.
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3 |
29038896
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ATF3 directly modulates the regulation of NFATc1 gene promoter activity and alters the expression of Wnt6 and Fzd9, direct target genes of NFATc1 signaling.
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4 |
29038896
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The ATF3 binding site of NFATc1 gene promoter is located at the region 671-775 base pairs upstream of the transcription start site.
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