Ignet

Gene Information

Gene symbol: TAGLN

Gene name: transgelin

HGNC ID: 11553

Synonyms: SM22, WS3-10, TAGLN1, SMCC, DKFZp686P11128

Related Genes

#	Gene Symbol	Number of hits
1	CASP3	1 hits
2	CDKN2B	1 hits
3	MYC	1 hits
4	SMAD3	1 hits
5	STAT3	1 hits

Related Sentences

#	PMID	Sentence
1	32583562	Smad3 signaling and transgelin expression are often activated during puromycin aminonucleoside (PAN)-induced podocyte injury.
2	32583562	The effects of SIS3 on the expression of the podocyte cytoskeletal proteins transgelin, p15^INK4B , phosphor-smad3, phosphor-JAK/stat3, the apoptotic marker cleaved caspase 3, and c-myc were investigated using western blot.
3	32583562	Transgelin expression and Smad3 phosphorylation were increased in the MPC5 cell line with prolonged PAN treatment.
4	32583562	In addition, c-myc expression, p15^INK4B , and JAK phosphorylation were all increased after treatment with PAN.
5	32583562	Moreover, stimulating podocytes directly with TGFβ-1 also led to enhanced expression of transgelin or phosphor-JAK/stat3, and this could be inhibited by SIS3.
6	32583562	In conclusion, transgelin expression was induced through the Smad3 signaling pathway during PAN-induced podocyte injury, and the resulting abnormal distribution of F-actin and the enhanced expression of transgelin could be reversed by blockade of this pathway.
7	32583562	Smad3 signaling and transgelin expression are often activated during puromycin aminonucleoside (PAN)-induced podocyte injury.
8	32583562	The effects of SIS3 on the expression of the podocyte cytoskeletal proteins transgelin, p15^INK4B , phosphor-smad3, phosphor-JAK/stat3, the apoptotic marker cleaved caspase 3, and c-myc were investigated using western blot.
9	32583562	Transgelin expression and Smad3 phosphorylation were increased in the MPC5 cell line with prolonged PAN treatment.
10	32583562	In addition, c-myc expression, p15^INK4B , and JAK phosphorylation were all increased after treatment with PAN.
11	32583562	Moreover, stimulating podocytes directly with TGFβ-1 also led to enhanced expression of transgelin or phosphor-JAK/stat3, and this could be inhibited by SIS3.
12	32583562	In conclusion, transgelin expression was induced through the Smad3 signaling pathway during PAN-induced podocyte injury, and the resulting abnormal distribution of F-actin and the enhanced expression of transgelin could be reversed by blockade of this pathway.
13	32583562	Smad3 signaling and transgelin expression are often activated during puromycin aminonucleoside (PAN)-induced podocyte injury.
14	32583562	The effects of SIS3 on the expression of the podocyte cytoskeletal proteins transgelin, p15^INK4B , phosphor-smad3, phosphor-JAK/stat3, the apoptotic marker cleaved caspase 3, and c-myc were investigated using western blot.
15	32583562	Transgelin expression and Smad3 phosphorylation were increased in the MPC5 cell line with prolonged PAN treatment.
16	32583562	In addition, c-myc expression, p15^INK4B , and JAK phosphorylation were all increased after treatment with PAN.
17	32583562	Moreover, stimulating podocytes directly with TGFβ-1 also led to enhanced expression of transgelin or phosphor-JAK/stat3, and this could be inhibited by SIS3.
18	32583562	In conclusion, transgelin expression was induced through the Smad3 signaling pathway during PAN-induced podocyte injury, and the resulting abnormal distribution of F-actin and the enhanced expression of transgelin could be reversed by blockade of this pathway.
19	32583562	Smad3 signaling and transgelin expression are often activated during puromycin aminonucleoside (PAN)-induced podocyte injury.
20	32583562	The effects of SIS3 on the expression of the podocyte cytoskeletal proteins transgelin, p15^INK4B , phosphor-smad3, phosphor-JAK/stat3, the apoptotic marker cleaved caspase 3, and c-myc were investigated using western blot.
21	32583562	Transgelin expression and Smad3 phosphorylation were increased in the MPC5 cell line with prolonged PAN treatment.
22	32583562	In addition, c-myc expression, p15^INK4B , and JAK phosphorylation were all increased after treatment with PAN.
23	32583562	Moreover, stimulating podocytes directly with TGFβ-1 also led to enhanced expression of transgelin or phosphor-JAK/stat3, and this could be inhibited by SIS3.
24	32583562	In conclusion, transgelin expression was induced through the Smad3 signaling pathway during PAN-induced podocyte injury, and the resulting abnormal distribution of F-actin and the enhanced expression of transgelin could be reversed by blockade of this pathway.
25	32583562	Smad3 signaling and transgelin expression are often activated during puromycin aminonucleoside (PAN)-induced podocyte injury.
26	32583562	The effects of SIS3 on the expression of the podocyte cytoskeletal proteins transgelin, p15^INK4B , phosphor-smad3, phosphor-JAK/stat3, the apoptotic marker cleaved caspase 3, and c-myc were investigated using western blot.
27	32583562	Transgelin expression and Smad3 phosphorylation were increased in the MPC5 cell line with prolonged PAN treatment.
28	32583562	In addition, c-myc expression, p15^INK4B , and JAK phosphorylation were all increased after treatment with PAN.
29	32583562	Moreover, stimulating podocytes directly with TGFβ-1 also led to enhanced expression of transgelin or phosphor-JAK/stat3, and this could be inhibited by SIS3.
30	32583562	In conclusion, transgelin expression was induced through the Smad3 signaling pathway during PAN-induced podocyte injury, and the resulting abnormal distribution of F-actin and the enhanced expression of transgelin could be reversed by blockade of this pathway.