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Gene Information

Gene symbol: TEC

Gene name: tec protein tyrosine kinase

HGNC ID: 11719

Synonyms: PSCTK4

Related Genes

# Gene Symbol Number of hits
1 FOS 1 hits
2 NPHS1 1 hits

Related Sentences

# PMID Sentence
1 12424224 Mutations of NPHS1 or NPHS2, the genes encoding for the glomerular podocyte proteins nephrin and podocin, cause steroid-resistant proteinuria.
2 12424224 Podocin interacts with the C-terminal domain of nephrin and facilitates nephrin-dependent signaling.
3 12424224 NEPH1 triggers AP-1 activation similarly to nephrin but requires the presence of Tec family kinases for efficient transactivation.
4 12424224 We conclude that NEPH1 defines a new family of podocin-binding molecules that are potential candidates for hereditary nephrotic syndromes not linked to either NPHS1 or NPHS2.