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Gene Information
Gene symbol: TLR5
Gene name: toll-like receptor 5
HGNC ID: 11851
Synonyms: TIL3, SLEB1, FLJ10052, MGC126430, MGC126431
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | TLR2 | 1 hits |
| 2 | TLR3 | 1 hits |
| 3 | TLR4 | 1 hits |
| 4 | TLR6 | 1 hits |
| 5 | TSLP | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 18256364 | Expression of TLR1 through 9 and TLR11 mRNA was detectable in whole kidneys and in isolated glomeruli of wild-type mice, with TLR3 and TLR4 having the highest absolute levels of expression. |
| 2 | 18256364 | TLR1, 2, and 4 were increased in TSLP transgenic mice and even higher in TSLP transgenic FcgammaRIIb-deficient mice. |
| 3 | 18256364 | TLR5 through 9 and 11 were upregulated to similar degrees in TSLP transgenic and TSLP transgenic FcgammaRIIb-deficient mice. |
| 4 | 23161414 | LPS also caused increased levels of IL-6, IL-8 and MCP1 without exerting any effect on TNF-α, IFN-α or TGF-β1 at 24 h. |
| 5 | 23161414 | In contrast, PAN-induced only small changes in the expression of TLRs 2-6 that included a persistent increase in TLRs 2 and 5, a transient increase in TLR-4, and a gradual increase in TLRs 3 and 6 between 1 and 6 h. |
| 6 | 23161414 | In summary, these novel findings show that LPS, a known TLR-4 ligand, induced the gene expression of multiple TLRs with maximum effect on the expression of TLR-1 suggesting a loss of receptor selectivity and induction of receptor interactions in podocytes. |