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Gene Information
Gene symbol: TTC21B
Gene name: tetratricopeptide repeat domain 21B
HGNC ID: 25660
Synonyms: FLJ11457, JBTS11, NPHP12, IFT139
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | APOL1 | 1 hits |
| 2 | ARHGAP24 | 1 hits |
| 3 | CLDN8 | 1 hits |
| 4 | COL4A3 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 27461219 | Nephropathy loci, including SLC7A9, UMOD, and SHROOM3, have been implicated in the maintenance of normal glomerular and renal tubular structure and function. |
| 2 | 27461219 | Meta-analysis of 4218 discovery and replication samples revealed three significant associations with T2D-ESKD at CD2AP and MMP2 (P corr < 0.05 corrected for effective number of SNPs in each locus). |
| 3 | 27461219 | Removal of APOL1 renal-risk genotype carriers revealed additional association at five loci, TTC21B, COL4A3, NPHP3-ACAD11, CLDN8, and ARHGAP24 (P corr < 0.05). |
| 4 | 27461219 | Genetic variants at COL4A3, CLDN8, and ARHGAP24 were potentially pathogenic. |