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Gene Information
Gene symbol: UBD
Gene name: ubiquitin D
HGNC ID: 18795
Synonyms: FAT10
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
31241995
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Cellular expression of two APOL1 RRVs has been demonstrated to induce cytotoxicity, including necrosis, apoptosis, and pyroptosis, in several cell types including podocytes; mechanistically, these toxicities were attributed to lysosomal swelling, K+ depletion, mitochondrial dysfunction, autophagy blockade, protein kinase receptor activation, ubiquitin D degradation, and endoplasmic reticulum stress; notably, these effects were found to be dose dependent and occurred only in overtly APOL1 RRV-expressing cells.
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