Ignet

Gene Information

Gene symbol: WASF2

Gene name: WAS protein family, member 2

HGNC ID: 12733

Synonyms: WAVE2, SCAR2

Related Genes

#	Gene Symbol	Number of hits
1	MAPK1	1 hits
2	NTRK3	1 hits

Related Sentences

#	PMID	Sentence
1	29162704	Tropomyosin-related kinase C (TrkC) enhances podocyte migration by ERK-mediated WAVE2 activation.
2	29162704	Activation of endogenous TrkC by its ligand neurotrophin-3 resulted in increased podocyte migration-a surrogate of podocyte actin dynamics in vivo.
3	29162704	Employing a mutagenesis approach, we found that the Src homologous and collagen-like (Shc) binding site Tyr⁵¹⁶ within the TrkC cytoplasmic domain was necessary for TrkC-induced migration of podocytes.
4	29162704	TrkC activation led to a mobility shift of Wiskott-Aldrich syndrome family verprolin-homologous protein (WAVE)-2 which is known to orchestrate Arp2/3 activation and actin polymerization.
5	29162704	Chemical inactivation of Erk or mutagenesis of 2 of 4 known Erk target sites within WAVE2, Thr³⁴⁶ and Ser³⁵¹, abolished the TrkC-induced WAVE2 mobility shift.
6	29162704	Knockdown of WAVE2 by shRNA abolished TrkC-induced podocyte migration.
7	29162704	In summary, TrkC signals to the podocyte actin cytoskeleton to induce migration by phosphorylating WAVE2 Erk dependently.
8	29162704	Tropomyosin-related kinase C (TrkC) enhances podocyte migration by ERK-mediated WAVE2 activation.
9	29162704	Activation of endogenous TrkC by its ligand neurotrophin-3 resulted in increased podocyte migration-a surrogate of podocyte actin dynamics in vivo.
10	29162704	Employing a mutagenesis approach, we found that the Src homologous and collagen-like (Shc) binding site Tyr⁵¹⁶ within the TrkC cytoplasmic domain was necessary for TrkC-induced migration of podocytes.
11	29162704	TrkC activation led to a mobility shift of Wiskott-Aldrich syndrome family verprolin-homologous protein (WAVE)-2 which is known to orchestrate Arp2/3 activation and actin polymerization.
12	29162704	Chemical inactivation of Erk or mutagenesis of 2 of 4 known Erk target sites within WAVE2, Thr³⁴⁶ and Ser³⁵¹, abolished the TrkC-induced WAVE2 mobility shift.
13	29162704	Knockdown of WAVE2 by shRNA abolished TrkC-induced podocyte migration.
14	29162704	In summary, TrkC signals to the podocyte actin cytoskeleton to induce migration by phosphorylating WAVE2 Erk dependently.
15	29162704	Tropomyosin-related kinase C (TrkC) enhances podocyte migration by ERK-mediated WAVE2 activation.
16	29162704	Activation of endogenous TrkC by its ligand neurotrophin-3 resulted in increased podocyte migration-a surrogate of podocyte actin dynamics in vivo.
17	29162704	Employing a mutagenesis approach, we found that the Src homologous and collagen-like (Shc) binding site Tyr⁵¹⁶ within the TrkC cytoplasmic domain was necessary for TrkC-induced migration of podocytes.
18	29162704	TrkC activation led to a mobility shift of Wiskott-Aldrich syndrome family verprolin-homologous protein (WAVE)-2 which is known to orchestrate Arp2/3 activation and actin polymerization.
19	29162704	Chemical inactivation of Erk or mutagenesis of 2 of 4 known Erk target sites within WAVE2, Thr³⁴⁶ and Ser³⁵¹, abolished the TrkC-induced WAVE2 mobility shift.
20	29162704	Knockdown of WAVE2 by shRNA abolished TrkC-induced podocyte migration.
21	29162704	In summary, TrkC signals to the podocyte actin cytoskeleton to induce migration by phosphorylating WAVE2 Erk dependently.
22	29162704	Tropomyosin-related kinase C (TrkC) enhances podocyte migration by ERK-mediated WAVE2 activation.
23	29162704	Activation of endogenous TrkC by its ligand neurotrophin-3 resulted in increased podocyte migration-a surrogate of podocyte actin dynamics in vivo.
24	29162704	Employing a mutagenesis approach, we found that the Src homologous and collagen-like (Shc) binding site Tyr⁵¹⁶ within the TrkC cytoplasmic domain was necessary for TrkC-induced migration of podocytes.
25	29162704	TrkC activation led to a mobility shift of Wiskott-Aldrich syndrome family verprolin-homologous protein (WAVE)-2 which is known to orchestrate Arp2/3 activation and actin polymerization.
26	29162704	Chemical inactivation of Erk or mutagenesis of 2 of 4 known Erk target sites within WAVE2, Thr³⁴⁶ and Ser³⁵¹, abolished the TrkC-induced WAVE2 mobility shift.
27	29162704	Knockdown of WAVE2 by shRNA abolished TrkC-induced podocyte migration.
28	29162704	In summary, TrkC signals to the podocyte actin cytoskeleton to induce migration by phosphorylating WAVE2 Erk dependently.
29	29162704	Tropomyosin-related kinase C (TrkC) enhances podocyte migration by ERK-mediated WAVE2 activation.
30	29162704	Activation of endogenous TrkC by its ligand neurotrophin-3 resulted in increased podocyte migration-a surrogate of podocyte actin dynamics in vivo.
31	29162704	Employing a mutagenesis approach, we found that the Src homologous and collagen-like (Shc) binding site Tyr⁵¹⁶ within the TrkC cytoplasmic domain was necessary for TrkC-induced migration of podocytes.
32	29162704	TrkC activation led to a mobility shift of Wiskott-Aldrich syndrome family verprolin-homologous protein (WAVE)-2 which is known to orchestrate Arp2/3 activation and actin polymerization.
33	29162704	Chemical inactivation of Erk or mutagenesis of 2 of 4 known Erk target sites within WAVE2, Thr³⁴⁶ and Ser³⁵¹, abolished the TrkC-induced WAVE2 mobility shift.
34	29162704	Knockdown of WAVE2 by shRNA abolished TrkC-induced podocyte migration.
35	29162704	In summary, TrkC signals to the podocyte actin cytoskeleton to induce migration by phosphorylating WAVE2 Erk dependently.