- About
- Home
- Introduction
- Statistics
- Programs
- Dignet
- Gene
- GenePair
- BioSummarAI
- Help & Docs
- Documents
- Help
- FAQs
- Links
- Acknowledge
- Disclaimer
- Contact Us
Gene Information
Gene symbol: WNK1
Gene name: WNK lysine deficient protein kinase 1
HGNC ID: 14540
Synonyms: HSAN2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | OXSR1 | 1 hits |
| 2 | STK39 | 1 hits |
| 3 | SYNPO | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 33604334 | WNK kinases and their target kinases oxidative stress-responsive kinase 1 (OSR1) and SPS1-related proline/alanine-rich kinase (SPAK) have fundamental roles in angiogenesis and are activated by calcineurin inhibitors, but the actions of these agents on kidney vasculature, and glomerular capillaries are not fully understood. |
| 2 | 33604334 | WNK1 and OSR1/SPAK are expressed in podocytes, and in a pattern similar to podocyte synaptopodin in glomerular capillaries. |
| 3 | 33604334 | Calcineurin inhibitors increased active OSR1/SPAK in glomerular capillaries, the Young's modulus (E) of glomeruli, and the F/G actin ratio, effects all blocked by WNK inhibition. |
| 4 | 33604334 | In cultured podocytes, FK506 activated OSR1/SPAK, increased lamellipodia, accelerated cell migration, and promoted traction force. |