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Gene Information

Gene symbol: ZNF318

Gene name: zinc finger protein 318

HGNC ID: 13578

Synonyms: HRIHFB2436, ZFP318

Related Genes

#	Gene Symbol	Number of hits
1	REN	1 hits

Related Sentences

#	PMID	Sentence
1	33671780	It is an efficient endocrine regulator of the Renin-Angiotensin-Aldosterone System (RAAS) and erythropoiesis, exerts immunomodulatory effects, reduces the cardiovascular events and all-cause mortality.
2	33671780	Moreover, Vitamin D major carrier, the D-binding protein (DBP), is less represented due to Nephrotic Syndrome (NS), proteinuria, and the alteration of the cubilin-megalin-amnionless receptor complex in the renal proximal tubule.
3	33671780	Activated Vitamin D has been demonstrated to potentiate the antiproteinuric effect of RAAS inhibitors in IgA nephropathy and Lupus Nephritis, enforcing its role in the treatment of glomerulonephritis: calcitriol treatment, through Vitamin D receptor (VDR) action, can regulate the heparanase promoter activity and modulate the urokinase receptor (uPAR), guaranteeing podocyte preservation.
4	33671780	It also controls the podocyte distribution by modulating mRNA synthesis and protein expression of nephrin and podocin.
5	33671780	Paricalcitol demonstrated a significant role in suppressing RAAS genes expression: it significantly decreases angiotensinogen, renin, renin receptors, and vascular endothelial growth factor (VEGF) mRNA levels, thus reducing proteinuria and renal damage.