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Gene Pair Information
Gene Pair: GLI1, IFNG
Related Sentences
| # |
PMID |
Sentence |
| 1 |
2081597
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Eight loci, including A2M, GLI, HOX3, IFNG, INT1, KRAS2, NKNB, and PAH, were assigned to the previously identified bovine syntenic group U3 represented by GAPD.
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| 2 |
2081597
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Additionally, the results predict that ALDH2 is distal to PAH and IFNG on HSA 12, the type II keratin gene complex will reside between q11 and q21 of HSA 12, A2M will map to MMU 6, and LALBA and GLI will map to MMU 15.
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| 3 |
8912848
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Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets.
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| 4 |
8912848
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The genes most frequently amplified and overexpressed were CDK4 (with coamplification of SAS) and MDM2.
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| 5 |
8912848
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Because individual malignant gliomas showed CDK4/SAS amplification but no MDM2 amplification and vice versa, the possibility remained of a common amplification target gene located between CDK4 and MDM2.
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| 6 |
8912848
|
All tumors and cell lines were analyzed at eight gene loci and six anonymous loci from 12q13-q15, including seven loci located between CDK4 and MDM2.
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| 7 |
8912848
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These studies revealed two centers of amplification, one at CDK4/SAS and the other at MDM2.
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| 8 |
8912848
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A number of loci located close to either MDM2 or CDK4/SAS, including the genes GADD153, GLI, RAP1B, A2MR, and IFNG, were found to be coamplified in some tumors but not overexpressed consistently.
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| 9 |
8912848
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All amplicons were discontinuous between CDK4/SAS and MDM2.
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| 10 |
8912848
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Our results thus exclude a common amplification target between CDK4/SAS and MDM2 and provide additional evidence that these genes represent two independent targets of selection.
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| 11 |
19302234
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K562/A02 cells showed a 65-fold higher IC(50) to adriamycin and less intracellular accumulation of adriamycin than K562. cDNA microarray showed marked increases in binding of collagen and cell proliferation-related genes (CD44, DLL3, IL17B, NUMB, and NUMBL) and decreases in signal transduction and transcription factor activity related genes (FZD9, GBP2, GLI1, GLI2, IFNG, KRT5, Notch2, and Notch3).
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