Ignet

Gene Pair: HPS1, MAS1

Related Sentences

#	PMID	Sentence
1	22098465	In animals, inflammatory lesions track with IFNγ and IL-10 expression and infection of Ifng(-/-) mice leads to increased pathogen load but inhibition of inflammation.
2	22098465	With severe disease, tissues can demonstrate hemophagocytosis, and measures of macrophage activation/hemophagocytic syndromes (MAS/HPS) support the concept of human granulocytic anaplasmosis as an immunopathologic disease.
3	22098465	MAS/HPS are related to defective cytotoxic lymphocytes that ordinarily diminish inflammation.
4	22098465	Pilot studies in mice show cytotoxic lymphocyte activation with A. phagocytophilum infection, yet suppression of cytotoxic responses from both NKT and CD8 cells, consistent with the development of MAS/HPS.