Ignet

Gene Pair: IFNG, HMGA1

Related Sentences

#	PMID	Sentence
1	15710911	IFN-gamma gene expression is controlled by the architectural transcription factor HMGA1.
2	15710911	This finding is supported by our direct studies of T cells isolated from the HMGA1-transgenic mice displaying an up-regulation of IFN-gamma production and of HMGA1-deficient mice exhibited a decreased IFN-gamma induction.
3	15710911	In parallel transfection studies in EL4 cells, we observed elevated IFNG gene promoter activity in cells stably over-expressing HMGA1 and a reduction of such activity in cells expressing dominant-negative HMGA1.
4	15710911	In vitro binding assays further demonstrated a specific interaction of HMGA1 to defined regions of the IFNG gene proximal promoter.