Ignet

Gene Pair: MMP3, TNFRSF11B

Related Sentences

#	PMID	Sentence
1	24222748	Local gene transfer of OPG prevents joint damage and disease progression in collagen-induced arthritis.
2	24222748	This study examined the influence of osteoprotegerin (OPG) gene transfer on a murine collagen-induced arthritis model.
3	24222748	MicroCT data suggested significant protection against subchondral bone mineral density changes in OPG treated CIA mice.
4	24222748	Interestingly, mRNA expressions of IFN-g and MMP3 were noticeably diminished following OPG gene transfer.
5	24222748	Overall, gene transfer of OPG effectively inhibited the arthritis-associated periarticular bone erosion and preserved the architecture of arthritic joints, and the study provides evidence that the cartilage protection of the OPG gene therapy may be associated with the down-regulation of MMP3 expression.