Ignet

Gene Pair: MYLK, TJP1

Related Sentences

#	PMID	Sentence
1	15194744	PAR2 activation alters colonic paracellular permeability in mice via IFN-gamma-dependent and -independent pathways.
2	15194744	We further investigated the possible involvement of interferon gamma (IFN-gamma) and calmodulin-dependent activation of myosin light chain kinase (MLCK), and alterations of zonula occludens-1 (ZO-1) localization in PAR(2)-induced responses.
3	15194744	Western blotting showed phosphorylation of mucosal myosin light chain (MLC) expression after both doses of SLIGRL.
4	15194744	Finally, we have shown that direct activation of PAR(2) on enterocytes is responsible for increased permeability and ZO-1 disruption.
5	15194744	The resulting tight junction opening does not depend upon IFN-gamma secretion, while the increased permeability in response to the high dose of PAR(2) agonist involves IFN-gamma secretion.