Ignet

Gene Pair: TNF, TNFRSF9

Related Sentences

#	PMID	Sentence
1	19017962	Self-antigen prevents CD8 T cell effector differentiation by CD134 and CD137 dual costimulation.
2	19017962	Enforced dual costimulation through OX40 and 4-1BB redirected CD8 cells encountering soluble exogenous peptide to expand and differentiate into IFN-gamma and TNF-alpha double-producing effectors rather than becoming tolerant.
3	19017962	Thus, the ability of enforced OX40 plus 4-1BB dual costimulation to redirect CD8 cells to undergo effector differentiation was unexpectedly influenced by the source of tolerizing Ag and help was selectively required to facilitate CD8 cell effector differentiation when the tolerizing Ag derived from self.