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Gene Pair Information
Gene Pair: TNFRSF9, TNF
Related Sentences
| # |
PMID |
Sentence |
| 1 |
19017962
|
Self-antigen prevents CD8 T cell effector differentiation by CD134 and CD137 dual costimulation.
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| 2 |
19017962
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Enforced dual costimulation through OX40 and 4-1BB redirected CD8 cells encountering soluble exogenous peptide to expand and differentiate into IFN-gamma and TNF-alpha double-producing effectors rather than becoming tolerant.
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| 3 |
19017962
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Thus, the ability of enforced OX40 plus 4-1BB dual costimulation to redirect CD8 cells to undergo effector differentiation was unexpectedly influenced by the source of tolerizing Ag and help was selectively required to facilitate CD8 cell effector differentiation when the tolerizing Ag derived from self.
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