Ignet

Gene Pair: CD2AP, LAMB2

Related Sentences

#	PMID	Sentence
1	10997929	CD2AP is expressed with nephrin in developing podocytes and is found widely in mature kidney and elsewhere.
2	10997929	CD2-associated protein (CD2AP) is an adapter molecule that can bind to the cytoplasmic domain of nephrin, a component of the glomerular slit diaphragm.
3	10997929	Mice lacking CD2AP exhibit a congenital nephrotic syndrome characterized by extensive foot process effacement, suggesting that CD2AP-nephrin interactions are critical to maintaining slit diaphragm function.
4	10997929	We have examined the patterns of expression of both CD2AP and nephrin in developing mouse and human kidney.
5	10997929	Kidneys from Cd2ap -/- mice initially exhibited normal nephrin localization, but as the mice aged and foot processes became effaced, nephrin disappeared.
6	10997929	In laminin-beta(2) mutant mice exhibiting nephrotic syndrome, CD2AP in glomeruli was aberrantly localized in a primarily punctate pattern.