Ignet

Gene Pair: LDLR, LRPAP1

Related Sentences

#	PMID	Sentence
1	7510321	Organ distribution in rats of two members of the low-density lipoprotein receptor gene family, gp330 and LRP/alpha 2MR, and the receptor-associated protein (RAP).
2	7510321	We investigated immunohistochemically the distribution in rats of the homologous proteins gp330 and the LDL receptor-related protein (LRP/alpha 2MR), and a receptor-associated protein (RAP), and the sites to which soluble exogenous RAP binds.
3	7510321	The only cells that clearly expressed both LRP/alpha 2MR and gp330 were retinal and ciliary epithelial cells.
4	7510321	RAP was found in intracellular vesicles in all cells that expressed gp330 or LRP/alpha 2MR.
5	7510321	Binding sites for RAP were found on the surface of those cells with surface gp330 or LRP, and also throughout the cytoplasm in cells with diffuse cellular LRP/alpha 2MR or gp330.
6	7510321	Because of their different locations, we conclude that gp330 and LRP/alpha 2MR serve distinct functions in vivo, despite similarities in ligand-binding properties observed in vitro.