Ignet

Gene Pair Information

Gene Pair: NUDT6, DES

Related Sentences

#	PMID	Sentence
1	8995747	Changes in glomerular epithelial cells induced by FGF2 and FGF2 neutralizing antibody in puromycin aminonucleoside nephropathy.
2	8995747	In the present study, two series of experiments were done with PAN nephropathy rats given fibroblast growth factor 2 (FGF2) or FGF2 neutralizing antibodies.
3	8995747	In the first series of experiments, a dose of 10 micrograms of FGF2 (FGF2 group), 40 micrograms of an FGF2 neutralizing antibody (Anti-FGF2 group) or an equal volume of physiological saline (Control group) was administered for four days after PAN injection.
4	8995747	Urinary protein increased more in the FGF2 group than in the other two groups.
5	8995747	PCNA (+) glomerular cells were found in decreasing order in groups FGF2, Control and Anti-FGF2.
6	8995747	Staining for desmin, a marker of podocyte injury, was significantly reduced in the Anti-FGF2 group.
7	8995747	Glomerular adhesive lesions were found in decreasing order in groups FGF2, Control and Anti-FGF2.
8	8995747	The second series of experiments was designed to study the effects of FGF2 neutralizing antibody (40 micrograms for 5 days after PAN injection, in MoAb group) on severely damaged podocytes caused by repeated (two courses) injections in the PAN nephropathy rats.
9	8995747	It was supposed that FGF2 would promote the formation of adhesive lesions by stimulating the proliferation of podocytes and epithelial cells of Bowman's capsule.
10	8995747	Additionally, FGF2 itself was thought to impair podocytes because of the increasing desmin score and proteinuria.