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Gene Pair Information
Gene Pair: WT1, PAX2
Related Sentences
| # |
PMID |
Sentence |
| 1 |
9916932
|
WT1 and PAX-2 podocyte expression in Denys-Drash syndrome and isolated diffuse mesangial sclerosis.
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| 2 |
9916932
|
One target gene of WT1 is PAX2, the expression of which is down-regulated in podocytes during early stages of nephrogenesis.
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| 3 |
9916932
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We demonstrate that WT1 mislocalization is associated with abnormal podocyte expression of PAX2 protein and RNA.
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| 4 |
9916932
|
We suggest that persistent expression of PAX2 is likely to result from the loss of WT1 dependent transcriptional repression and may participate in the pathological mechanisms leading to glomerular dysfunction.
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| 5 |
9916932
|
Abnormal distribution of WT1 and PAX2 was also observed in isolated diffuse mesangial sclerosis suggesting that a defect in WT1 could also be operative in isolated diffuse mesangial sclerosis.
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