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Gene Information
Gene symbol: FASLG
Gene name: Fas ligand (TNF superfamily, member 6)
HGNC ID: 11936
Synonyms: FasL, CD178
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BIRC5 | 1 hits |
| 2 | CD40LG | 1 hits |
| 3 | FAS | 1 hits |
| 4 | IFNG | 1 hits |
| 5 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20720169 | Proapoptotic factor Fas ligand (FASL) and its cell surface receptor FAS are tumor necrosis factor superfamily members that trigger apoptosis in different cell types. |
| 2 | 20720169 | The aim of the present work was to determine (i) the presence of the cytokine FASL and its receptor FAS in the mare's corpus luteum (CL) throughout the luteal phase, as well as (ii) the influence of FASL alone, or together with the cytokines tumor necrosis factor alpha (TNF) and interferon gamma (IFNG), on equine luteal cell production of luteotrophic and luteolytic factors, cell viability, and apoptosis. |
| 3 | 20720169 | Furthermore, FASL effect on equine luteal cell viability depended on the presence of cytokines TNF and IFNG. |
| 4 | 20959405 | We found several genotypes associated with complete cytogenetic response: IFNG (rs1861494, rs2069705), FASL (rs763110), FAS (rs2234767, rs2234978), VEGFR2 (rs1531289), and WT1 (rs2234590); with major molecular response: IFNG (rs1861494, rs2069705), BIRC5 (rs9904341), FAS (rs2234978), and ABCG2 (rs2231142); with loss of response: IFNG (rs2069705), IFNGR2 (rs9808753), BIRC5 (rs9904341), and ORM (rs3182041); and with treatment failure: IFNG (rs2069705), JAK3 (rs3212713), and ORM (rs3182041). |
| 5 | 21976969 | Microarray and qRT-PCR data analyses showed significant upregulation of some cytotoxicity-related genes, including those from the granzyme family, tumor necrosis factor, Fas Ligand, and chemokines, in the spleen cells of IFNg KO mice. |