Statistics
Ignet has analyzed abstracts from millions of publications available in PubMed.
Specifically, Ignet has found 573167 gene-gene interactions from 360283 sentences in 219004 PubMed publications. These interactions involve 11817 unique human genes.
An example listed for gene interaction with IFNG:
1473 genes associated with IFNG,
Top 50 genes ranked by four scores
Rank |
Degree centrality |
Eigenvector centrality |
Closeness centrality |
Betweenness centrality |
1 |
NOS2A |
MME |
GPR98 |
PLAT |
2 |
VEGFA |
TAC1 |
CNBP |
ID2 |
3 |
EGF |
ERBB2 |
CUBN |
IL6 |
4 |
ERBB2 |
EGF |
CSPG4 |
SOD1 |
5 |
EGFR |
EGFR |
CXADR |
MITF |
6 |
ZFP36 |
VEGFA |
FEV |
CD4 |
7 |
SRC |
NOS2A |
KATNB1 |
ERBB2 |
8 |
SPINK1 |
POMC |
DAO |
SRC |
9 |
PRSS1 |
AVP |
TFAP2B |
IL2 |
10 |
PRSS3 |
NPPA |
IRX3 |
EGFR |
11 |
ID2 |
ZFP36 |
SCN1A |
IFNG |
12 |
DCX |
DCX |
PFKL |
IRF4 |
13 |
NGF |
NGF |
RDX |
PTEN |
14 |
POMC |
ID2 |
NTN4 |
VWF |
15 |
AVP |
PLAT |
EPHA7 |
PPARG |
16 |
PLAT |
SRC |
ISCU |
CD8A |
17 |
NPPA |
PRSS1 |
GPS1 |
AGT |
18 |
MME |
SPINK1 |
VEZT |
MS |
19 |
TAC1 |
PRSS3 |
MIRN124-3 |
TNF |
20 |
IL6 |
EPO |
THAP5 |
EPO |
21 |
LYN |
IL6 |
AP2B1 |
ABL1 |
22 |
BMI1 |
KIT |
BCAR3 |
IL4 |
23 |
CD4 |
SST |
PDZD7 |
AKT1 |
24 |
TNF |
COL1A1 |
SLC5A3 |
SGK1 |
25 |
EPO |
PPARG |
TPST2 |
DNMT1 |
26 |
IFNG |
NKX2-5 |
GAL |
REN |
27 |
PPARG |
TBX5 |
KIF1B |
CASP3 |
28 |
MITF |
SERPINE1 |
ALAS1 |
MCL1 |
29 |
SOD1 |
PLG |
MELAS |
GJA1 |
30 |
PDGFA |
CSF1 |
ALDH5A1 |
TNFSF10 |
31 |
KIT |
TNFSF11 |
DLL4 |
CLS |
32 |
SST |
NFKB1 |
CKS2 |
TSC2 |
33 |
COL1A1 |
PDGFB |
MCF2L |
MPO |
34 |
NKX2-5 |
BCR |
EFNA5 |
AVP |
35 |
TBX5 |
SLC47A2 |
TSIX |
MAPK1 |
36 |
SERPINE1 |
SLC22A2 |
IRX6 |
INS |
37 |
PLG |
ABL1 |
MIRN122 |
COL1A1 |
38 |
IL2 |
CYP2B6 |
SLC6A1 |
SST |
39 |
MS |
ALPI |
PDLIM4 |
IL2RA |
40 |
MAPK1 |
TBXAS1 |
TRDMT1 |
IL5 |
41 |
CD8A |
PTH |
MCOLN3 |
POMC |
42 |
VWF |
IL2 |
AKR1D1 |
NPPA |
43 |
CRP |
IL2RA |
TRPV4 |
MET |
44 |
HBB |
CYP3A4 |
LRP2 |
NPR1 |
45 |
INS |
CYP1A1 |
PSMD10 |
ACE |
46 |
FAM126A |
IL10 |
CDK7 |
PDGFA |
47 |
STAT3 |
REN |
HDAC11 |
VEGFA |
48 |
IL4 |
SELL |
HADHB |
NOS2A |
49 |
PTEN |
TIMP1 |
SETD1B |
TSC1 |
50 |
IRF4 |
ELN |
SETD1A |
MUC5AC |