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Statistics

Ignet has analyzed abstracts from millions of publications available in PubMed.

Specifically, Ignet has found 573167 gene-gene interactions from 360283 sentences in 219004 PubMed publications. These interactions involve 11817 unique human genes.


An example listed for gene interaction with IFNG:

1473 genes associated with IFNG,

Top 50 genes ranked by four scores

Rank Degree centrality Eigenvector centrality Closeness centrality Betweenness centrality
1 NOS2A MME GPR98 PLAT
2 VEGFA TAC1 CNBP ID2
3 EGF ERBB2 CUBN IL6
4 ERBB2 EGF CSPG4 SOD1
5 EGFR EGFR CXADR MITF
6 ZFP36 VEGFA FEV CD4
7 SRC NOS2A KATNB1 ERBB2
8 SPINK1 POMC DAO SRC
9 PRSS1 AVP TFAP2B IL2
10 PRSS3 NPPA IRX3 EGFR
11 ID2 ZFP36 SCN1A IFNG
12 DCX DCX PFKL IRF4
13 NGF NGF RDX PTEN
14 POMC ID2 NTN4 VWF
15 AVP PLAT EPHA7 PPARG
16 PLAT SRC ISCU CD8A
17 NPPA PRSS1 GPS1 AGT
18 MME SPINK1 VEZT MS
19 TAC1 PRSS3 MIRN124-3 TNF
20 IL6 EPO THAP5 EPO
21 LYN IL6 AP2B1 ABL1
22 BMI1 KIT BCAR3 IL4
23 CD4 SST PDZD7 AKT1
24 TNF COL1A1 SLC5A3 SGK1
25 EPO PPARG TPST2 DNMT1
26 IFNG NKX2-5 GAL REN
27 PPARG TBX5 KIF1B CASP3
28 MITF SERPINE1 ALAS1 MCL1
29 SOD1 PLG MELAS GJA1
30 PDGFA CSF1 ALDH5A1 TNFSF10
31 KIT TNFSF11 DLL4 CLS
32 SST NFKB1 CKS2 TSC2
33 COL1A1 PDGFB MCF2L MPO
34 NKX2-5 BCR EFNA5 AVP
35 TBX5 SLC47A2 TSIX MAPK1
36 SERPINE1 SLC22A2 IRX6 INS
37 PLG ABL1 MIRN122 COL1A1
38 IL2 CYP2B6 SLC6A1 SST
39 MS ALPI PDLIM4 IL2RA
40 MAPK1 TBXAS1 TRDMT1 IL5
41 CD8A PTH MCOLN3 POMC
42 VWF IL2 AKR1D1 NPPA
43 CRP IL2RA TRPV4 MET
44 HBB CYP3A4 LRP2 NPR1
45 INS CYP1A1 PSMD10 ACE
46 FAM126A IL10 CDK7 PDGFA
47 STAT3 REN HDAC11 VEGFA
48 IL4 SELL HADHB NOS2A
49 PTEN TIMP1 SETD1B TSC1
50 IRF4 ELN SETD1A MUC5AC