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Gene Information
Gene symbol: IL18
Gene name: interleukin 18 (interferon-gamma-inducing factor)
HGNC ID: 5986
Synonyms: IGIF, IL1F4, IL-1g, IL-18
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | IFNG | 1 hits |
| 2 | IL12A | 1 hits |
| 3 | INDO | 1 hits |
| 4 | NFKBIZ | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20876105 | Analysis of Nfkbiz(-/-) mice revealed that I?B? was essential for the production of IFN-? production and cytotoxic activity in NK cells in response to IL-12 and/or IL-18 stimulation. |
| 2 | 20876105 | IL-12/IL-18-mediated gene induction was profoundly impaired in Nfkbiz(-/-) NK cells. |
| 3 | 21118329 | We propose that an increase in interleukin-18, and its associated induction of indoleamine 2, 3-dioxygenase and quinolinic acid, mediates seizure activity in MS at least in part via an increase in interferon-gamma (IFNg). |
| 4 | 21321581 | Activation of splenic T lymphocytes derived from protected mice in vitro with pharmacological agents that bypass the antigen receptor or immobilized anti-CD3 antibody resulted in enhanced expression of Ifng mRNA and protein without altering the expression of Il4, Il17, Il18, Inos and Tnfa genes nor the secretion of IL-2, IL-4, IL-17 and TNF-? proteins. |