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Gene Information
Gene symbol: IL2
Gene name: interleukin 2
HGNC ID: 6001
Synonyms: IL-2, TCGF
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD28 | 1 hits |
| 2 | CD4 | 1 hits |
| 3 | CD8A | 1 hits |
| 4 | IDUA | 1 hits |
| 5 | IFNG | 1 hits |
| 6 | IL4 | 1 hits |
| 7 | MUC1 | 1 hits |
| 8 | NCAM1 | 1 hits |
| 9 | PHF11 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21321581 | Activation of splenic T lymphocytes derived from protected mice in vitro with pharmacological agents that bypass the antigen receptor or immobilized anti-CD3 antibody resulted in enhanced expression of Ifng mRNA and protein without altering the expression of Il4, Il17, Il18, Inos and Tnfa genes nor the secretion of IL-2, IL-4, IL-17 and TNF-? proteins. |
| 2 | 20724768 | to find out the the influence of iron on the levels of plasma IL-2 and IFNgamma in iron deficiency anemia patient. the study subjects were patients with IDA (intended samples) selected from the accessible population that met the inclusion and exclusion criteria using consecutive sampling technique and by signing an informed consent. |
| 3 | 20724768 | Before treatment level of plasma IL-2 was 7.65 pg/l then became 29.3 pg/l after treatment (Z=- 3.508, p<0.001) and plasma IFNg before treatment was 10.15 pg/l became 46.7 pg/l after treatment (Z= -4.241, p<0.001). concentration of IL2 dan IFNgamma in plasma significantly increased after administration of iron tablets for 8 weeks as compared to that before iron treatment. |
| 4 | 20421878 | In contrast, small-interfering RNA knock-down of PHF11 decreased transcription of both IFNG and IL2 and led to decreased CD28 cell-surface expression and reduced NF-?B nuclear import and DNA binding. |
| 5 | 7663570 | Lymph nodes containing microscopic tumor and shed mucin exhibited approximately 40-fold expansion in short-term (< 21 days) cultures with either IL-2 or IL-1 plus IL-2; the combination of IL-2/anti-CD3 monoclonal antibody (mAb) resulted in significantly higher expansion. |
| 6 | 7663570 | Cultures generated with IL-2 alone favored the expansion of CD8+ and CD56+ cells, whereas addition of IL-1 or anti-CD3 mAb to IL-2 promoted outgrowth of CD4+ T-cells. |
| 7 | 7663570 | In addition, CD4+ cells expressed mRNA for IL-2, IL-4, tumor necrosis factor-beta and IFNg, and retained the ability to secrete IL-2 after expansion. |
| 8 | 8389732 | In the present study we have evaluated the ability of 1,25-(OH)2D3 to affect proliferation and cytokine production by human T cell lines stimulated by anti-CD3 antibodies or anti-CD3 plus anti-CD28 antibodies. 1,25-(OH)2D3 selectively reduced the supernatant levels of IL-2, while the IFNg and LT levels were unaffected. |