Gene Information
Gene symbol: JAK3
Gene name: Janus kinase 3
HGNC ID: 6193
Synonyms: L-JAK, JAKL, LJAK, JAK3_HUMAN, JAK-3
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
18549798
|
In the absence of Jak3-dependent signals, naive CD4+ T cells proliferate robustly but produce little IFN-gamma after Th1 cell polarization in vitro.
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2 |
18549798
|
Instead, we find that T-bet binding to the Ifng promoter is greatly diminished in the absence of Jak3-dependent signals, correlating with a decrease in Ifng promoter accessibility and histone acetylation.
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