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Gene Information
Gene symbol: ACE
Gene name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
HGNC ID: 2707
Synonyms: ACE1, CD143
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ERBB2 | 1 hits |
| 2 | HLA-A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15164233 | Peptide extracts derived from primary HLA-A*0201-positive (+) HER-2/neu+ human tumors by acid elution (acid cell extracts (ACEs)) were tested for their capacity to elicit in HLA-A*0201 transgenic mice, cytotoxic T lymphocytes (CTLs) lysing HLA-A*0201+ HER-2/neu+ tumor cells. |
| 2 | 15164233 | Cytotoxicity of such ACE-induced CTL lines was directed, at least as detected herein, also against the HER-2/ neu peptides HER-2 (9(369)) and HER-2 (9(435)) demonstrating the immunodominance of these epitopes. |
| 3 | 15164233 | However, CTLs induced by ACEs displayed enhanced efficacy in the therapy of xenografted SCID mice compared with the HER-2 peptide-specific CTLs (i.e., HER-2 [9(369)] or HER-2 [9(435)]). |