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Gene Information
Gene symbol: C19orf10
Gene name: chromosome 19 open reading frame 10
HGNC ID: 16948
Synonyms: R33729_1, IL25, SF20, IL-25, IL-27
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD4 | 1 hits |
| 2 | IL10 | 1 hits |
| 3 | IL12A | 1 hits |
| 4 | IL13 | 1 hits |
| 5 | IL17A | 1 hits |
| 6 | IL4 | 1 hits |
| 7 | TGFB1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16369012 | Three heterodimeric cytokines, interleukin-12 (IL-12), IL-23, and IL-27, as well as IL-18, contribute to the differentiation and expansion of naive CD4(+) T cells. |
| 2 | 16369012 | In initial experiments, M. tuberculosis infection of DCs was more potent at inducing IL-12 and IL-23 secretion than infection with the vaccine strain Mycobacterium bovis bacille Calmette-Guérin (BCG), and no significant upregulation of IL-27 was observed. |
| 3 | 18684965 | Mice receiving either subset showed reduced disease incidence and low clinical scores; however, mice receiving total CD4(+) T cells showed delayed disease onset by 10 days with reduced clinical scores, reduced IL-17 and IL-27, but enhanced IL-4, IL-10, IL-13, and TGF-beta. |
| 4 | 21389257 | The in vitro results indicated that IL-10 produced by B cells and IL-10-promoting molecules such as IFN-? and IL-27 by dendritic cells are the major player for SA-2-driven IL-17A (and also IFN-? and IL-13) inhibition. |
| 5 | 21389257 | The in vivo experiments with anti-cytokine receptor Abs provided evidence of an early IL-17A inhibition essentially due to IL-10 produced by resident peritoneal cells and of a delayed IL-17A inhibition sustained by IFN-? and IL-27, which in turn drive effector T cells to IL-10 production. |