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Gene Information
Gene symbol: CAMP
Gene name: cathelicidin antimicrobial peptide
HGNC ID: 1472
Synonyms: CAP18, FALL39, FALL-39, LL37
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | APCS | 1 hits |
| 2 | CXCL10 | 1 hits |
| 3 | IL6 | 1 hits |
| 4 | IL8 | 1 hits |
| 5 | MAPK1 | 1 hits |
| 6 | MAPK14 | 1 hits |
| 7 | TLR4 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 18579695 | Thus, these results indicate that the MEK1/2 and p38 MAPK signaling pathways play a critical role in the regulation of inducible LL-37 gene expression in A549 cells infected with M. bovis BCG. |
| 2 | 21049021 | LL-37 neutralized the pro-inflammatory activity of endotoxin-free CPS as assessed by TLR2 and TLR4-MD-2-dependent release of TNF?, IL-6 and IL-8 from human and murine macrophages. |
| 3 | 21049021 | LL-37 also inhibited the ability of meningococcal CPS to induce nitric oxide release, as well as TNF? and CXCL10 (IP-10) release from TLR4-sufficient and TLR4-deficient murine macrophages. |
| 4 | 21278351 | Using human promonocytic cell line THP-1-derived macrophages as a cell model, we found that cells incubated with a hSAP-DNA complex showed significant defects in innate immune activations, whereas mouse SAP had similar, albeit very weak, activities. hSAP also significantly inhibited the functions of two identified DNA sentinels, high-mobility group B protein 1 and antimicrobial peptide LL37, and redirected DNA update to FcRs leading to endocytosis and endosomal degradation. |